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EPOR 抗体 (N-Term)

This anti-EPOR antibody is a 兔 多克隆 antibody detecting EPOR in WB. Suitable for 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马 和 山羊.
产品编号 ABIN2781766
发货至: 中国

Quick Overview for EPOR 抗体 (N-Term) (ABIN2781766)

抗原

EPOR (Erythropoietin Receptor (EPOR))

适用

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人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 山羊

宿主

  • 97
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  • 1

克隆类型

  • 104
  • 21
  • 1
多克隆

标记

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This EPOR antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL

    预测反应

    Cow: 85%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against EPOR. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human EPOR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 508 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    EPOR (Erythropoietin Receptor (EPOR))

    别名

    EPOR

    背景

    The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC138358, EPO-R
    Protein Interaction Partner: PIK3R1, SRC, MST1R, JAK2, SH2B2, STAT5A, CBL, CRKL, GRB2, UBC, SOCS2, PLCG1, INPP5D, CISH, NOSIP, ATXN2L, GAB2, GAB1, GRAP, STAT5B, SOCS3, MAPK3, IRS2, SHC1, PLCG2, SYK, KITLG, GNB2L1, MAPK1, PTPN6, PTPN11, KLK3, LYN, KIT, VAV1, GNAI1, CSF2RB, EPOR, EPO,
    Protein Size: 508

    分子量

    53 kDa

    基因ID

    2057

    NCBI登录号

    NM_000121, NP_000112

    UniProt

    P19235

    途径

    JAK/STAT Signaling
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